I am looking to buy Cortisol MIPs to use them in my research, I have seen a website can provide it but the price was too high ( 70k £). If you know any companies can provide this MIPs service please let me know.
They are generally easy to fabricate . Are you sure that option is not available for you? If you are making something like an electrochemical MIP , you do not even need to have a complex lab setup.
Muqsit Minhaj Pirzada thank you for your reply, my background is Microbiology I have no idea how to fabricate MIPs . If you can provide me any sources of MIPs fabrication methods it will be highly appropriated
Abdulaziz Zamkah Sure. It depends on your final application too to some extent. Generally, for electrochemical MIPs, depending on your analyte, yopu can choose electropolymerizable monomers such as dopamine, scopoletin, orthophenylene diamine, etc. Depending on your template molecule, you can either add it to the monomer mixture or immobilize it on the surface prior to polymerization (What i did in Article Cancer biomarker detection in human serum samples using nano...
) Finally you can remove the template by several methods such as electroxidation, chemical cleavage by incubation, etc. You can also develop nanoMIP which are generally reusable (
Chapter Applications of Molecularly Imprinted Nanostructures in Bios...
) Let me know if you need to know anything further.
Dear Muqsit Minhaj Pirzada Thank you for sharing me your paper and your useful advice and tips. I am going to read them now and try to do my best to understand the steps. I appreciate your valuable reply.