25 October 2016 0 9K Report

Deletion of 20 nucleotide before 5' UTR and complete deletion of 5'UTR and start codon and half part of exon part.

I want to know that if transcription will be continued (the promotor might  be work  and also because of some exception for Nonsense mediated decay in exon one) and also translation started (even without 5’UTR and their possible translational initiation factors, I don’t know it would be possible or not?)

Is it correct t say that the Ribosome will be start to search for finding the first Methionine in 3 possible frame and will be start translation based on it?

What is your idea about this scenario ? Based on your experience,it could be happened or not?

Thank you in advance.

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