How long before the surgery do you stop aspirin/clopidogrel etc.,?
Our anaesthetists prefer to stop Aspirin 3-5 days and Clopidogrel 5-7 days before the schedule Orthopaedic surgery under regional (spinal/epidural) anaesthesia
Perioperative Management of Patients on Antiplatelet Therapy:
1. Patients with coronary stents:
Elective surgery postponed for the following durations if aspirin and thienopyridine (eg, clopidogrel) therapy must be discontinued-
Bare metal stents: 4-6 wk
Drug-eluting stents: 12 months
If surgery cannot be postponed, continue aspirin throughout perioperative period
2. Patients at high risk for cardiac events (exclusive of coronary stents):
Continue aspirin throughout the perioperative period
Discontinue clopidogrel at least 5 d (and preferably 10 d) before surgery
Resume clopidogrel 24 hrs postoperatively
3. Patients at low risk of cardiac events:
Discontinue antiplatelet therapy 7Y10 d before surgery
Resume antiplatelet therapy 24 hrs postoperatively
Adapted from ASRA guidelines on "Regional Anesthesia in the Patient Receiving Antithrombotic or Thrombolytic Therapy".
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