"Lactose is the most important carbohydrate of the milk of most species. Its biosynthesis takes place in the mammary gland. Concentrations in milk vary strongly with species. Lactose is the first and only carbohydrate every newborn mammal (including human) consumes in significant amounts. Bovine milk contains 45 – 50 grams lactose per liter. Industrially lactose is produced from bovine milk exclusively, or rather from milk derivatives like cheese whey or ultra filtration permeate. Lactose is also known as milk sugar".
www.dfepharma.com/en/downloads.aspx?id=%7B2BB38A30-33EC...
"Lactose is the most important carbohydrate of the milk of most species. Its biosynthesis takes place in the mammary gland. Concentrations in milk vary strongly with species. Lactose is the first and only carbohydrate every newborn mammal (including human) consumes in significant amounts. Bovine milk contains 45 – 50 grams lactose per liter. Industrially lactose is produced from bovine milk exclusively, or rather from milk derivatives like cheese whey or ultra filtration permeate. Lactose is also known as milk sugar".
www.dfepharma.com/en/downloads.aspx?id=%7B2BB38A30-33EC...
Dear Hanno,
It seems there is a server error, may be due to some typing error as you said. I apologize for this inconvenience. I will try to download the file which is available on the internet in the same link, and send it to you.
lactose in solid dosage form were used as filler or bulking agent, to enhance the compressibility and fluidity, spray drier lactose were developed for direct compression of tablet process, ultrafine lactose is also used for powder inhalation and to enhance the solubility and dispersibility of poorly water-soluble drug on interactive mixture.
Lactose is ubiquitous in Pharmaceutical Science and has many functions. For example it used as a bulking agent / diluent in tablets and as a carrier particle in formulations used in the older types of dry powder inhalers. It is generally regarded as safe, i.e. it is a GRAS excipient and has a long history of use. Interestingly the solid forms of lactose are often miss appropriated in the literature as different polymorphs. They actually have different chemical structures and should be referred to as epimers. Please see a couple of my papers attached that address this issue.
Regards Paul
Article The Measurement of the β/α Anomer Composition Within Amorpho...
Article Stability of Sugar Solutions: A Novel Study of the Epimeriza...
Thank you very much for you answer.
Can we use sucrose in very small amount and the rest is kept Lactose ?
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