What is the risk of thrombophlebitis following infusion of 25 or 50% dextrose via peripheral line during IVGTT or clamp study? Any published data?

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Victor C. Kok

Hi, Negar,

Answer to your question particularly in the clamp study is seemingly not available in the literature. Attached is the article as a consolation prize.

Jayaprakash Subramani

Any hypertonic solution if infused through peripheral vein will cause thrombophlebitis.Risk depends on amount,frequency and duration of infusion. But the risk is almost 100% if infused for more than 48 hrs. For IV bolus of hypertonic solution, risk is certainly very low.