Hi, Negar, 

Answer to your question particularly in the clamp study is seemingly not available in the literature. Attached is the article as a consolation prize. 

Any hypertonic solution if infused through peripheral vein will cause thrombophlebitis.Risk depends on amount,frequency and duration of infusion. But the risk is almost 100% if infused for more than 48 hrs. For IV bolus of hypertonic solution, risk is certainly very low.