Hello,
I would like to predict the rate of heat diffusion through in vivo medium by LITT technique , I do not know which range of power would be used for this purpose, I would appreciate to get any source or link.
Hi!
LITT tissue coagulation typically uses 4-10 watts of continuous radiation at a wavelength of 1064 nm for diffusing noncooled probes. Liquid-cooled probes can also use up to 20 watts for diffusing probes. Data are given for a 20 mm scattering length, the most common length for diffusion scattering medical probes. The main criterion for choosing the maximum power is that there is no carbonization of the tissue around the probe. Carbon is good at absorbing laser radiation, re-radiating it into heat and reducing the efficiency of the coagulation process. I suggest studying Gerhard J. Müller, André Roggan Laser-induced Interstitial Thermotherapy SPIE Press, 1995. In spite of the year of publication, much in it is still relevant.
Hi Bazhdar
For primary and metastatic brain tumors that are difficult to reach with standard surgery, LITT is a developing approach. An implantable laser catheter is inserted into the tumor and heated to destroy the tumor. Probe design was lacking sufficient cooling and insulation to protect tissue traversed by the laser probe, limiting lasers to a power of 1–5 watts. I advice you to read the following article as it is very recent.
Mo Med, vol. 117(1); Jan-Feb 2020, PMC7023945
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