I have to study for Invitro progressive Ph(1.2,4.5,6.8.7.4) release for Meloxicam loaded sodiumalginate Microspheres by using USP-Apparatus 2 (Paddle Apparatus),during the study can i convert Ph 1.2 to Ph 4.5, Ph4.5 to Ph 6.8 and Ph6.8 to Ph 7.4 and how i will convert it ? And what time interval, i should select for Invitro progressive drug relase study ?