What is the nanoparticle size cut-off for intracellular application? Is there any comprehensive review regarding this?

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Oommen P Oommen

Size below 10 nm can diffuse into any cells. Ideally, size above 20 nm and lower than 150 nm. Please read the review article from Mark Davis in Nature reviews 2008, 7, 771 titled 'Nanoparticle therapeutics: an emerging treatment modality for cancer'

Size, shape and surface charge play a key role in delivery of nanoparticle and prevention if opsonization.

Filip Rázga

Thanx for suggestion