Breast cancer cells are known to rely on anaerobic metabolism for energy production, leading to the accumulation of lactate. This lactate-rich environment can promote tumor growth and metastasis. Exercise has been shown to have anti-tumor effects in breast cancer, and some studies have suggested that this may be due to its ability to reduce intratumoral lactate levels. However, the specific effects of different types of exercise on intratumoral lactate regulation are not well understood.
This research question aims to investigate the impact of high-intensity interval training (HIIT) and strength training on intratumoral lactate regulation in breast cancer. We hypothesize that both HIIT and strength training will reduce intratumoral lactate levels, but that the effects of HIIT will be more pronounced.