In 2012, there were 78 million new instances of gonorrhea among adults, making it the second most prevalent bacterial STI in the world. Infertility, pelvic inflammatory disease, ectopic pregnancy, and other consequences and sequelae of gonorrhoeic can occur if it is left untreated. Due to this, it's critical to understand what the most accurate method is for identifying Neisseria gonorrhoeae infection in a certain person. In this manner, an accurate diagnostic and quality control for the test in question can be accomplished.
Reference:
Cole, M. J., Quaye, N., Jacobsson, S., Day, M., Fagan, E., Ison, C., Pitt, R., Seaton, S., Woodford, N., Stary, A., Pleininger, S., Crucitti, T., Hunjak, B., Maikanti, P., Hoffmann, S., Viktorova, J., Buder, S., Kohl, P., Tzelepi, E., . . . Unemo, M. (2019, March 25). Ten years of external quality assessment (EQA) of Neisseria gonorrhoeae antimicrobial susceptibility testing in Europe elucidate high reliability of data. BMC Infectious Diseases, 19(1). https://doi.org/10.1186/s12879-019-3900-z
Molecular tests are the gold standard for diagnosing N. gonorrhoeae which can be performed in the lab or at the point of care. The agar dilution method is said to be the gold standard method for antimicrobial susceptibility testing in Ng. according to WHO.
Meyer T, Buder S. The Laboratory Diagnosis of Neisseria gonorrhoeae: Current Testing and Future Demands. Pathogens. 2020 Jan 31;9(2):91. doi: 10.3390/pathogens9020091. PMID: 32024032; PMCID: PMC7169389.