What is the best statistical test to compare 4 groups in 10 different time points.
Fecal parasitic egg count levels were determined in 1 week intervals from day 0 to 70.
Vaccine 1- Day 0
Vaccine 2- Day 35
Challenge infection- Day 49
Day 70 -trial ended
Group 1- vac1+vac 2+challenge
Group 2 - vac1+vac2 only
Group 3- challenge only
Group 4- control group
Determine the main research question and hypotheses related to the effects of vaccination, challenge infection, and time on fecal parasitic egg count levels.
Repeated Measures ANOVA:Conduct a repeated measures ANOVA with "Group" as the between-subjects factor (Group 1, Group 2, Group 3, Group 4) and "Time" as the within-subjects factor (10 time points).
- Include the interaction term between Group and Time to assess whether the treatment effects vary across time.
- Use statistical software like R, Python (with packages like SciPy and Statsmodels), or dedicated statistical packages (e.g., SPSS) to conduct the analysis.
- Interpret the results, considering both statistical significance and practical significance. Discuss the implications of the findings in the context of your research question.
Thank you very much for your Jonathan Ngugi valuable explanation.
- Badges
- Science topic
- Similar topics
- Analytical Chemistry
- Column