- SPM (especially 3D presentation in display modality)

- Brain Voyager

- Free Surfer

- MRIcron

Furthermore, it is possibile to show neuroimaging results with 3D presentation with AMIRA software (http://www.vsg3d.com/amira/overview) (you can upload your SPM results plot on standard 3D T1 MRI (i.e. colin27brain from MRIcron: ch2better.nii). See for example: Borroni B 2009, PMID: 19690415.

3D slicer is also really good, but probably needs some time to get familiar with:

http://www.slicer.org/

Any one recognizes what software can create this figure?

mricrogl (Google it), which is also by Chris Rorden of mricron fame. mricrogl is much easier than mricron for 3D data. You will need to create the gray+white matter mask using other software; in SPM, could can segment then create a brain mask by adding and thresholding (e.g, >0.5) the gray and white compartments. You would open this in mricrogl, then add the blobs (also saved as a nifti file).

The batch/script mode has some relatively simple examples you could edit for your data, in order to better control the display properties.

I'm not sure if mricrogl works on anything other than Windows.

Update below from Zhiguo: it does work on Linux & Mac.

Thanks Paul. Nice seeing you here. Microgl works on Linux and Mac as well. I use them very often in combining with 3dslicer. SPM does a decent job in 3D visulization but lack many fine control. In this regard, I vote for Mricrogl. LONI has an excellent tool, ShapeViewer. if you know how to use it, it can be very handy tool. But it only works with Mesh file (not for 3D volume data).

Thank you very much, Paul! I will try mricroGL for my rendering!

That image looks like it is a screen capture of the 3D rendering in FSLVIEW. Caret and Freesurfer both do nice jobs of presenting the data. The big downside for them is that they expect data to have been analyzed on a cortical surface rather than in a volume. You can get your volume data to their formats, but due to volume rather than surface smoothing sometimes your clusters can be split in usual manners on the inflated surfaces.

There are for sure a multitude of tools that can be used to get this kind of 3D-rendering. In my experience, Caret ( http://brainvis.wustl.edu/wiki/index.php/Caret:Documentation ) is doing a pretty good job, you just have to spend a little time figuring out what is the best "mapping algorithm" to show your results onto the surface.

Anatomist ( http://brainvisa.info/ ) is also nice, but maybe a bit harder to get familiar with.