Normally image labeler in Matlab works like ROI (Region of Interest) in ENVI or AOI (Area of Interest) in Erdas to select classes for training a classification algorithm. You can create your own custom vector of image labels by using the following tool
I did not understand your question very well you mean by labeling is to create classes to train a segmentation method? If that is the case than you need to create labels interactively from the image. Otherwise, I would suggest using unsupervised segmentation method with higher number of labels and you can then obtain your 5 classes in different ways. Please correct me if misunderstood your problem.