Dear colleagues, I am currently working on a manuscript addressing CIED pocket irrigation. I am looking into metanalyses regarding antiseptic and antibiotic solutions inside the pacemaker-pocket. Although approx. 60-80% of CIED implanting centres are using something inside the pocket, there is almost no literature on this matter. Solutions I am looking into are ethanol, PVP-iodine, chlorhexidine, polyhexanide, octenidine, taurolidine, hypochlorous acid, hydrogen peroxide and antibiotic solutions/sponges/envelopes.
I am familiar with big trials like PADIT, WRAPT-IT and the following:
https://europepmc.org/article/med/19790020
https://academic.oup.com/europace/article/19/suppl_3/iii306/3873166
https://online.boneandjoint.org.uk/doi/abs/10.1302/1358-992X.2019.14.084
https://onlinelibrary.wiley.com/doi/abs/10.1111/1574-695X.12005?sid=nlm:pubmed
Article The Impact of Povidone-Iodine Pocket Irrigation Use on Pacem...
Article Effect of pocket irrigation with antimicrobial on prevention...
Article Rapid Degradation and Non-Selectivity of Dakin's Solution Pr...
Article Effect of intraoperative local application of 3% hydrogen pe...
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Do you have suggestions? Are you among the centres using something inside the pocket?
What are you using?
Thank you.