1. Exaggerated hypoxic pulmonary vasoconstriction and pulmonary hypertension

2. Increased capillary pressure and pulmonary capillary hypertension

3. High permeability due to ‘stress failure’ of the pulmonary capillaries

4. Reduced fluid clearance from the alveolar space

Ref: Article High altitude pulmonary edema‑clinical features, pathophysio...

Regards- Rabiul.