As ‘Big Questions’ I would like to name those which are fundamental to the physical understanding of our Universe, such as: Why is the Universe made of matter rather than antimatter? What is the nature of Dark Matter, and of Dark Energy? Is there a preferred reference frame to the Universe? How are the forces of nature, including gravity, unified?

For decades, the primary experimental tools for addressing such Big Questions were large particle accelerators. However, scaling of these facilities to higher energies and larger sizes has become increasingly difficult and expensive—and may soon be impossible.

The conjecture I would like to discuss is: What can we learn from small-scale, low-cost terrestrial experiments in which subtle signs of new physics are sought through extreme sensitivity and precision?

Searches for tiny deviations from “ordinary” physical laws can be interpreted as tests of the very structure of the physical world. Examples might include the braking of symmetries like time reversal symmetry, or the search for a variation of the fundamental constants of nature like fine stricture constant or searches for a deviatipn from the 1/r law for the gravitational potential.

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