What can be used to dissolve Doxorubicin?

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Can i do protein expression of Toll-like receptor 4 cloned in pET-22B in E.coli cell?

Can

08 July 2024 6,725 4 View

Can anyone direct me to a best practice resource site on Prevention of Campus Sexual violence?

Following a baseline study on epidemiology of university campus sexual assault and findings that it is 3 times higher than in the general population I am working towards developing relevant and...

24 January 2020 4,266 4 View

Dear Researchers. Can anyone assist me access the treatment acceptability questionnaire?

I am currently involved in a study that wants to test new approaches to the management of diabetes 2 and hypertension in a LMIC. Part of the study is to assess acceptability of the proposed...

23 December 2018 2,907 3 View

Does anyone have or know of research tools on abuse of male children that I can adapt?

I am in the process of writing a mixed methods research proposal on abuse of male adolescents.Specifically I want to find out types of abuse they experience, their magnitude, and factors...

03 December 2015 9,333 3 View

Molecular biology protein expression

Hi everyone. I'm new to molecular biology and want to ask a question on protein expression. My next task is to express a Toll like receptor 4 protein cloned in E.coli cell. Is it possible to...

01 January 1970 9,729 0 View

Molecular biology cloning

Hi Everyone. I am new to molecular biology. I am currently doing ligation and transformation. What I did was I did a blunt end ligation of my inserts which is 1257 base pairs to my vector which is...

01 January 1970 692 6 View

Does 3T3-L1 or H9C2 cell line can be used for atherosclerosis model study?

I am designing research related to atherosclerosis in vitro, but unfortunately the cell lines currently available in our laboratory are only 3T3-L1 and H9C2, Does anyone can suggest me what...

17 July 2024 6,373 1 View

How to calculate percentage cumulative drug release?

How to calculate percentage cumulative drug release when, Total volume of dissolution media = 250ml Added formulation was equivalent to 10mg of drug Sample withdrawn = 1ml each time Sink condition...

15 July 2024 4,192 1 View

How validate the dynamic molecualr simulation with experimental data?

I used forcite module of Material Studio software to simulate the dissolution of zinc production waste in deep eutectic solvent. UFF force field has been used for the optimization of molecules,...

02 July 2024 7,491 1 View

After training an XGBoost model using K-fold cross-validation, Can I use SHAP to interpret this dataset?

In other words, I did not use the trained XGBoost model to make predictions on the test set and then use SHAP for interpretation. The reasons are as follows: Even with the best and most...

26 June 2024 7,332 1 View

What could dissolve MgO nanoparticles over time?

I have a set-up were I have a bottle with water (DI water, 0.8uS/cm). To that bottle I have added some MgO nanopowder, at a concentration of ~ 0.08mg/ml. It appears that the white powder is...

04 June 2024 9,787 4 View

Is it easier to couple polypeptides after a few days of dissolving them in PBS?

I want to couple the polypeptide to a cell culture plate, is it easier to couple the polypeptide after a few days of dissolution in PBS?

21 May 2024 9,683 1 View

How to dissolve Span 80 in mineral oil or liquid paraffin?

I want to work on microfluidic chip. Dispersed phase of alginate solution and continuous phase of Span 80 solution in combination with mineral oil or liquid paraffin. But I had a problem with the...

19 May 2024 1,790 7 View

How does the pKa of the drug affect the selection of dissolution medium for its release?

How does Handersen Hasselbach equation affect this selection?

28 April 2024 5,804 2 View

Which remediation methods for groundwater and soil pollution lead to precipitation/dissolution ?

Nowadays, many remediation methods have been applied to the remediation of groundwater and soil, including physical, chemical, biological, in-situ and ex-situ. Which of these methods involves the...

22 April 2024 6,836 0 View

Why does the doxorubicin in pbs solutions are giving variable spectrophotometric readings at similar concentrations and similar pH?

Variable readings at same time point and similar solutions

21 April 2024 743 0 View