I have a natural polymer extracted from natural sources. I made a cross linking reaction, so the polymer turned completely unsoluble.
I want to know what are the physical data that i have to determine for this polymer?
How can I charactrize it?
As told above, you can go for XRD, FTIR, NMR, XPS for structural analysis. For stability check, you can opt TGA, DSC etc. As you are working on drug delivery system, the knowledge about particle size may be a crucial factor and for that, you should go for TEM (Transmission electron microscopy) analysis.
Hi Mazin,
characterizations depend mainly on the field of application of your material. For example, in agro-food field, migration and volatility tests are the most necessary.
Thanks for your co operation
I want to use it in a drug delivers system.
As told above, you can go for XRD, FTIR, NMR, XPS for structural analysis. For stability check, you can opt TGA, DSC etc. As you are working on drug delivery system, the knowledge about particle size may be a crucial factor and for that, you should go for TEM (Transmission electron microscopy) analysis.
As it is already mentioned by others, the characterizations depend on the application. FTIR will confirm the structure, XRD will reveal the crystallographic data. NMR, XPS are also helpful. For morphology, you can go for SEM and/or TEM, AFM (if available). For thermal properties you can go for DSC and TGA. Fr drug delivery system you can also check the swelling ratio and characterize with UV-vis.
For coatings applications there are a lot of other practical tests....sol/gel fractions,Tg of natural polymer as well as crosslinker and Tg of crosslinked sample. Time/temperature of cure and measurements of hardness,flexibility.....
Hi, first of all you need to identify the application. Are you considering applying these materials to make membrane technology for gas separation or water desalination? Anyway, I would recommend to start with TGA, DSC, H-NMR and GPC, which is a characterization that you will likely need for most of the applications of interest.
Hello.
As mentioned by different experts you need to use different characterisation techniques / methods to establish the consistency of the manufacturing process for the said insoluble polymer.
Secondly, one needs to evaluate the suitability of the said polymer by living organism.
Hello. If you have got a crosslinked polymer, you can define it`s Мс - molecular weight between crosslinks (The molecular weight of chain length between cross-link points).
Recommended references:
1. Shape-Memory Polymers / Volume Editor A. Lendlein // Advances in Polymer Science: Splinger London New York – 2010. – Vol. 226. -. 2010. – Р.104-105/
2. Oleg Suberlyak,Oleksandr Grytsenko and Victoria Kochubei. The role of FeSO4 in the obtaining of polyvinylpirolidone copolymers // Chemistry & Chemical Technology. – 2015, 9(4) P.429 – 434.
3. Murat Sen, Arzu Yakar, Olgun Guven Polymer. Determination of average molecular weight between cross-links (Mc) from swelling behaviours of diprotic acid-containing hydrogels // Polymer. – 1999, 40, P. 2969–2974.
please, there is no insoluble polymer ???????? All is possible except the devision by zero ????????. Malgres that XRD, GPC, DSC give information on the product synthetizes but the most beautiful is HNMR ?????? therefore the solubility problem has to be solved for example, an ionic product must be prepared as the solvent.
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