What are the reasons in selecting subjects in the age range of 38-60 years ain a research involving immunology and haematology?

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Ellen S Vitetta

Adults in this age range are immunologically and hematologically mature and “ normal”. Prior to age 18 these systems are often considered less mature .....PLUS using pediatric individuals is another issues. Both systems decline after age 60.

Sven Reister

In aedition to Ellen's post you have the ethical consideration which is more difficult to obtain samples from individuals younger than 18. For 60+ you will ready face stem cell exhaustion and shift towards myeloid lineage

Tomasz Grabowski

Dear all,

Some nice explanation of 60 cut-off explain full versions of paper below:

Article Elderly patients' participation in clinical trials

Best regards

Tomasz

Yes, I hope things continue to evolve this way. Geriatric populations should br studied too. It’s not so different than the way we used to exclude women from clinical trials!!! Progress is slow.....and advocacy helps.