Numbers of peroxovanadium compounds have been reported over the years, which have insuline-like properties. Is it possible to use one of them as an alternative to Insuline? What will be the toxicity of the vanadium?
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The main question is the ratio of EC (effective concentration) and and LD50 values (lethal dose) in the case of each compounds. The other thing is, the LD50 values of the metabolites. Vanadium is a heavy metal, and the peroxo group is a reactive species, so transformation and metabolization will probably be fast. ALso important question is the character of the ligand, whether it can keep the vanadium to be non-ionic (it has chance that a non-toxic) form after the metabolization or not.
So, the simple answer is hard, there are important factors which should be studied before answering.
Thank you László Kótai for your valuable suggestion and comments.
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