We generally recommend good foods. Best are the use of olive oil, biological and citrus juices. Reduction of harmful foods.

Dear Dr Hairi Ismaili Many thanks for your kind contribution and valuable answer.

My sincere gratitude.

In fact there are several means, both lifestyle and pharmaceutical, to raise plasma HDL-C level and hence enhancing it's anti-atherogenic properties. Among the lifestyle approaches, exercising regular moderate intensity physical activity is very effective in raising plasma HDL-C levels. other lifestyle measures include weight reduction and avoidance of cigarette smoking which is associated with reduced HDL-C concentrations.

Pharmacologically, Statins which are lipid lowering agents are also very effective in inducing several favorable effects on lipid and lipoprotein profile including significant improvement in plasma HDL-C in patients with low levels.

Hi Dr Salman K. Ajlan . A major mechanism by which these treatments are thought to delay progression or cause regression of atherosclerosis is by promoting efflux of cholesterol from macrophage foam cells. In addition, HDL has been described as having anti-inflammatory and other beneficial effects. See the link: Article Anti-Atherogenic Mechanisms of High Density Lipoprotein: Eff...

Also, see the following link: https://academic.oup.com/cardiovascres/article/103/3/341/2931035

Kindly , see the following link too: https://www.ajconline.org/article/S0002-9149(98)00808-X/abstract

According to what Dr. Salman mentioned, statins are useful for lowering bad cholesterol... Does this mean that it is possible to take this drug to also help in weight loss?

Dear Dr Aref Wazwaz Many thank for your valuable contribution and important answer with regard to the anti-atherogenic properties of HDL and the potentiation of their effects. My sincere gratitude.

Dear Dr Aref Wazwaz Many thanks for sharing valuable links to enrich this discussion. Best regards.

You are most welcome dear

Dr Salman K. Ajlan .

Wish you the best always.

Dear ميسم شهاب Statins, lipid lowering agents are not indicated for inducing weight loss. However, They are primarily indicated for managing dyslipidaemia, specifically elevated total cholesterol, LDL-C, and low HDL-C levels. Statins are extensively uesd for the primary and secondary prevention of cardiovascular disease. Many Thanks for your kind contribution and comment. My sincere gratitude.

Dear Dr Aref Wazwaz We are so grateful for your valuable participation that greatly enriched this discussion. I wish you all the best. My sincere gratitude.

Thank you very much Salman Ajlan for this valuable information

Dear ميسم شهاب You are most welcome. Many thanks for your valuable contribution. Best regards.

In addition to its role in regulating reverse cholesterol transport, many studies have shown that HDL may also have antiatherogenic properties. Indeed, HDL decreases endothelium inflammation and oxidative stress and increases nitric oxide production and endothelial cell (EC) survival, thus preventing atherogenesis.

Dear Enas Tariq Khudair Really you have presented valuable answer with regard to favorable effects of HDL including its anti-atherogenic properties with which I agree in depth. Many thanks for your valuable contribution. My sincere gratitude.

Interested

Dear Dr Azhar Azher Mohammed Al-Ankoshy Many thanks for your kind contribution and reply. My sincere gratitude.

Dear Dr بيداء عبد السلام مهدي

شكرا" جزيلا" على مشاركتكم القيمة مع خالص تمنياتي بالصحة الدائمة والنجاح والتوفيق

Based on the following study it has been concluded that HDLs have multiple functions beyond their ability to promote the efflux of cholesterol from cells and also these properties have the clear potential to contribute to the antiatherogenic effects of HDL.

Article Antiinflammatory Properties of HDL

Also, based on the following study it has been found that HDL represents a lipoprotein particle capable of acquiring potentially toxic proatherogenic lipids and restricting them to an environment where they can be safely inactivated and/or from which they can be delivered to the liver for excretion.

Article Antioxidant capacity of high-density lipoprotein (HDL): Mech...

Also, check the following RG link that may be useful:

Article High-Density Lipoprotein Function and Dysfunction in Health ...

Dear Dr Manal Hadi Kanaan. Many thanks for your valuable replies illustrating diverse beneficial effects of HDL with special emphasis to its anti-atherogenic properties. My sincere gratitude

Dear Dr Manal Hadi Kanaan. Many thanks for attaching valuable links to enrich this discussion. My best wishes.

It is my pleasure Dear Dr. Salman K. Ajlan My sincere gratitude

Dear Dr Manal Hadi Kanaan. We are so grateful for your valuable participation which greatly enriched this discussion. I wish you all the best. Kind regards.

The use of healthy foods and olive oil in addition to green tea, lemon, ginger and cloves, all of this will help in possible to augment the anti-atherogenic effect of HDL

Dear Rana Waleed Many thanks for your kind contribution and valuable reply. My sincere gratitude.

Dear Pr Salman Ajlan,

I recommend you to read this article:

Article The metabolism and ant-atherogenic properties of HDL

Best regards,

Pr Hambaba

Check https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234332/

Also check https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674714/

Dear Dr Salman K. Ajlan . See the following useful RG link: Article Anti-Atherogenic Mechanisms of High Density Lipoprotein: Eff...

Kindly see also the following link: https://www.ajconline.org/article/S0002-9149(98)00808-X/abstract

Dear Dr Leila Hambaba. Many thanks for your kind contribution and valuable reply. Many thanks too for sharing valuable article. My sincere gratitude.

Dear Dr Chinaza Godswill Awuchi. Many thanks for your kind contribution and sharing valuable links to enrich this discussion. My sincere gratitude.

Dear Dr Aref Wazwaz. Thank you so much for your kind contribution and sharing valuable links to enrich the discussion. Best regards.

Also check on this paper.

Article Interaction between adipocytes and high-density lipoprotein:...

Dear Dr Kiprotich Kiptum. Many thanks for your kind contribution and sharing valuable link. My sincere gratitude.

افضل شيء الرياضة المستمرة

Dear Dr ابراهيم سلمان الموسوي.. Yes I agree with you that exercising regular physical training results in raising plasma HDL level and potentiating it's anti-atherogenic effect. Many thanks for your valuable contribution and comment. My sincere gratitude.

animal ghee is increase HDL and Exercise is the best thing .

Dear Dr. Nooralhuda Alfatlawi I agree with you that regular exercise causes an increase in HDL level. Many thanks for your kind contribution and reply. My sincere gratitude.

Machine Epsilon is a machine-dependent floating point value that provides an upper bound on the relative error due to rounding in floating point arithmetic. Mathematically, for each floating point type, it is equivalent to the difference between 1.0 and the smallest representable value that is greater than 1.0.

Dear doctor

This is the abstract of a study done by Murphy et al. (2012):

"In some settings increasing high density lipoprotein (HDL) levels has been associated with a reduction in experimental atherosclerosis. This has been most clearly seen in apolipoprotein A-I (apoA-I) transgenic mice or in animals infused with HDL or its apolipoproteins. A major mechanism by which these treatments are thought to delay progression or cause regression of atherosclerosis is by promoting efflux of cholesterol from macrophage foam cells. In addition, HDL has been described as having anti-inflammatory and other beneficial effects. Some recent research has linked anti-inflammatory effects to cholesterol efflux pathways but likely multiple mechanisms are involved. Macrophage cholesterol efflux may have a role in facilitating emigration of macrophages from lesions during regression. While macrophages can mediate cholesterol efflux by several pathways, studies in knockout mice or cells point to the importance of active efflux mediated by ATP binding cassette transporter (ABC) A1 and G1. In addition to traditional roles in macrophages, these transporters have been implicated in the control of hematopoietic stem cell proliferation, monocytosis and neutrophilia, as well as activation of monocytes and neutrophils. Thus, HDL and cholesterol efflux pathways may have important anti-atherogenic effects at all stages of the myeloid cell/monocyte/dendritic cell/macrophage lifecycle."

Dear Dr Sundus F Hantoosh Many thanks for your valuable reply regarding the anti-atherogenic effect of HDL that enriched this discussion. My sincere gratitude.