i'm working on amelioration of neurotoxicity produced by long term and low dose of exposure of xenobiotics ,
please help and provide any links and papers.
i think that this paper can help you :
Effects of Deltamethrin on striatum and hippocampus mitochondrial integrity and the protective role of Quercetin in rats. May 2017. Environmental Science and Pollution Research 24(6)
another paper wos attached. good luck
Detoxification of xenobiotics is mainly done by enzyme called glutathione S transferase which catalyzed the conjugation of reduced glutathione GSH with the xenobiotics and converted the xenobiotics from water insoluble to water soluble which can be easily excreted with the urine we done research in this subject which is available in my RG
good luck in your endeavor
Hello,
Agreed with Dr Abdelrahim Ahmad Hunaiti
Furthermore, There r other enzymes as Detoxification of xenobiotics including: Cytochrome P450, Hydrolyzing and DDT-Dehydrochlorinase DDTases are as metabolic Detoxificating on Xenobiotics. These enzymes do detoxification types of prevalent pesticides, But metabolism for all of pesticides doesnt mean detoxifaction. This is important for Organophosphorus pesticides because metabolism caused activating of Organophosphorus compounds.
Also, there r many articles about this subject.
U see this links:
Article Enzymatic detoxification of organophosphorus pesticides and ...
Article Detoxification of Organophosphate Poisoning Using Nanopartic...
Article Detoxification of the organophosphate nerve agent coumaphos ...
The Best Regards
Samaneh Mahmoudvand
Thank you so much for the help @ Kebsa Wided , Abdelrahim Ahmad Hunaiti , Samaneh Mahmoudvand .
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