Threshold represents the minimum detectable concentration or amount of an analyte, while signal-to-noise ratio measures the relative strength of the analyte signal compared to the background noise.
The threshold is basically the noise level. If the level is defined, everything above it can be considered as a signal.
The signal-to-noise ratio (S/N) indicates peaks from the analytes to the noise in the sample. It is determined by comparing the measured signals from the analytes with the blank sample. S/N =10:1 is considered normal. S/N between 2:1 and 3:1 is generally considered acceptable for evaluating the LOD (limit of detection).