I would say navigation, either on urban or non-urban environments, that can add some changes to the daily activity that routes us from house to work/school to shopping: walking, cycling, driving or sailing, out of / expanding the daily routine surrounding environment. And perhaps also using external imagery like maps in paper or smart devices with LBS (Location Based Services) and possibly AR (Augmented Reality), that can reference or inform the place and the corresponding bodily experience, spatial cognition and the mental imagery of the surrounding environment. If all this can be reproduced in a complete VR (Virtual Reality) environment, is an issue that is being study by Neurosciences and Design, and maybe there is not a definite answer ...
Conference Paper Space time information on display: smart devices and spatial cognition
I have created a type of exercise called Brain Body Mastery which integrates juggling, plyometrics (athletic agility training), and mental/visual math. I believe it is exactly what you're looking for. It's like those brain-training computer programs but in 3D and with the body. The idea is basically to find separate activities that use different parts of the brain/body and integrate them into complex activities. Anyone can do this on their own. All you need is curiosity and courage. Below are some video examples.