In the world of journal publications, rejections are the norm rather than the exception. So, what are the common causes for manuscript rejection and how to deal with it?
However, one must remember that rejection of a research paper by a journal should not be the end of the world. Journals do not like submitted articles that are not formatted correctly. Attention should be given to the 'authors instructions' available on all journal web sites, such that the submitted manuscript design should equate with that of the journal. Avoid plagiarism, ensure grammatical fluency, include a statement of study limitations, provide a contemporary reference list and make sure your data are accurate and are reproduced accurately in abstract, text, tables and figures. The journal editor may provide additional information in their response letter explaining a specific reason that the manuscript was not considered for review. This information can be very helpful to consider when choosing another journal.
With my little experience rejection is inevitable if the the content of the paper is not within the scope of the journal. Please carefully go through aims and scopes of each journal; if within the scope of the journal many other reasons including not abiding to instructions found under authors instructions; the content is not scientifically sound to be published, some reject specific types of paper such as case reports if they think they don't add much on current literature, sometimes not because the paper is not good but the journal decide to be very selective or because they are overwhelmed with papers.
I learnt to move to the next journal and improve the paper with whatever comments I would get from those journals.
I believe there are many such paper not structured as required by the journal; the journals decide to be very selective because of limited resources for some free open access journals. Or simply because the paper is not scientifically sound for publication in their journal.