what are the reaction conditions and precautions to be taken?
Kumar,
Please, clarify your question (request) with a given equation to be able to help you.
Good luck
Must to use reaction known as Robinson annulation.
a) C. H. Heathcock, J. E. Ellis, J. E. McMurry, A. Coppolino, Tetrahedron Lett., 1971, 12, 4995. DOI
b) C. H. Heathcock, C. Mahaim, M. F. Schlecht, T. Utawanit, J. Org. Chem., 1984, 49, 3264.
dipolar cycloaddition to the alpha, beta unsaturatation...........either azomethine ylide or nitrone will make, pyrrolizidine/pyrrolidine and isoxazolidine type of compounds.
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