What are the best reagents to make fused heterocyclics for a compound containing an alpha beta unsaturated ketone ?

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Can anyone suggest me the basic infrastructure required for study of cancer biology and drug development?

the instruments required and techniques used in cancer laboratory

08 September 2016 4,980 3 View

What is the exact mechanism in the solvent induced transformation of stereo isomers?

I have observed the transformation (from Z to E) in a steroid moiety after a long standing with a mixture of polar solvents. Can you please explain me the mechanism, I mean how and what...

02 March 2016 6,428 2 View

What is the best season for collecting plant parts for the phytochemical screening?

does season of collection depends on the type of plant part going to be screened?

03 April 2015 5,873 16 View

What type of chemical constituents can we expect from root and bark from the Spp. of Boraginaceae family?

I am planning to isolate phytochemicals from the root and bark extract of plants belonging to boraginaceae family so, please tell me what type of phytoconstituents I can expect.?

08 September 2014 9,218 9 View

Why is the surface of some non-aquatic plant leaves hydrophobic?

Is there any relation (chemically) with the bioactive-constituents present in that particular plant, irrespective of their water loss etc.?

06 July 2013 4,130 4 View

How to overcome the formation of fungus on aqueous plant extract solutions?

09 October 2012 4,715 10 View

• What the possible Persistent Organic Pollutants and Heavy metals present in fluorspar, sediments, and water bodies around its mining area?

Approximate concentrations are require in compared with the WHO permissible limts

11 August 2024 2,723 1 View

Basis set and input instruction to calculate HOMO and LUMO using Orca for Imidazolium based organic salts?

Hey there, As a synthetic chemist delving into theoretical calculations for my imidazolium-based organic molecules, I would greatly appreciate any guidance on the appropriate input instructions...

09 August 2024 5,444 7 View

How to calculate CCS for Sodiated adduct ions and Multiply Charged Ions?

I'm currently working on calculating the collision cross section (CCS) for various ions, and I'm facing challenges when dealing with sodiated and multiply charged ions. Most of the resources I’ve...

08 August 2024 8,329 0 View

Separation of organic acids-HPLC?

Hello What should be done to separate and identify organic acids in HPC when their RetTime is the same?Like oxalic acid with Propanoic Acid.or acids that have a very close RetTime.

07 August 2024 8,782 3 View

Can I multiplex a mouse monoclonal and rat primary for IHC (mouse brain tissue)?

Hi all, I was just wondering if anyone has experience with multiplexing a mouse monoclonal primary and a rat primary. I'm trying to multiplex by incubating them in the same well but was told by a...

06 August 2024 9,710 1 View

Interested in a SCOPUS collaboration?

Hi RG family. My team and I are working on some SCOPUS publications and we need co-authors who are willing and capable of undertaking both qualitative and quantitative-based studies. The scope...

02 August 2024 7,843 0 View

How to convert g/kg Humic acid dose to kg/ha?

I used humic acid at 0.044 g/kg soil in my pot experiment. But finally, I have to recommend kg/ha. Each pot's soil weight was 11 kg. What is the solution?

02 August 2024 7,186 6 View

Interested in a SCOPUS collaboration?

Hi RG family. My team and I are working on some SCOPUS publications and we need co-authors who are willing and capable of undertaking both qualitative and quantitative-based studies. The scope of...

02 August 2024 8,572 0 View

Does anyone have issues using Prepman Ultra reagent for MicroSeq ID bacterial, fungal and yeast sample preparation?

I have been attempting to extract DNA from Bacterial, Fungal and Yeast banked samples (>1e7 cells) using Prepman Ultra reagent and I seem to be struggling to obtain a sequence. Although the...

01 August 2024 2,079 0 View

How to improve peaks separation in HPLC?

Hi everyone, I'd like to better separate two close peaks coming from a bioconversion sample, I'm currently using a C18 KromaPhase 4,6mm Ø.I. SCHARLAU, particle size (µm): 10, pore size (Å): 100,...

30 July 2024 435 3 View

Adel Amer

Kumar,

Please, clarify your question (request) with a given equation to be able to help you.

Good luck

Rossen Buyukliev

Must to use reaction known as Robinson annulation.

a) C. H. Heathcock, J. E. Ellis, J. E. McMurry, A. Coppolino, Tetrahedron Lett., 1971, 12, 4995. DOI

b) C. H. Heathcock, C. Mahaim, M. F. Schlecht, T. Utawanit, J. Org. Chem., 1984, 49, 3264.

Abhijit Hazra

dipolar cycloaddition to the alpha, beta unsaturatation...........either azomethine ylide or nitrone will make, pyrrolizidine/pyrrolidine and isoxazolidine type of compounds.