What are the best doses to use in an animal experiment to determine the toxicity and therapeutic dose of the crude plant extract?

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How can I go about in silico studies using chemical compound identified in fraction from column chromatography using HPLC or GCM-M?

I want see if there is interaction with compounds characterised with either HPLC or GCM-M with any proteins in silico

31 December 2018 8,568 3 View

Can one remove slovent from nonpolar solvent extract through Lyophilization ?

lyophilizer can remove non polar solvent from extract just as with water

08 September 2018 7,160 2 View

Can i get a youtube link or any material on the use of graph pad prism ?

most statistical analysis or graph in my study are done using SPSS but i want to explore the use of graph pad prism.

04 May 2017 3,399 1 View

Can I get materials, jornal papers or links that can help in learning and mastering the use of PyMOL ?

I need the the latest application of the software application for the antimalarial principle identification in my study. I need more enlightenment on the usefulness in toxicological studies

04 May 2017 8,206 1 View

How can one synthesize ZnO naonoparticle using ZnO salt which is insoluble in water and aqueous laef extract?

The experiment is green synthesis of ZnO nanoparticle using aqueous extract.

08 September 2016 1,701 3 View

What is the ratio of plant extract to salt in green synthesis of nanomaterials?

this is to know the proportion of the extract that should be added to the salt to use for green synthesis

10 November 2015 3,635 4 View

How effective is calcination in nanomaterial green synthesis and which other methods could be preferred?

temperature and pH is an important factors in green synthesis, what synthetic procedure should be used to get the active nanomaterial

10 November 2015 9,371 7 View

Which statistical package should be preferred for more accurate result for biological experiments?

best statistical package for statistical analysis

06 July 2015 8,449 0 View

Can anyone send to me any publication or book on chemoinformatics and bioinformatic?

this to enhance my knowledge on this concepts

04 May 2015 5,227 0 View

Can one identify an unculturable microorganism using meta-genomic technique?

a fermentation of our local seed were fermented and we have some suspicious that certain other micro-organism could be responsible and want see if meta-genomic technique be useful in confirming it

04 May 2015 2,030 1 View

What are the long-term impacts of incarceration on youths' developing brain?

I want to explore the long-term effects of incarceration on a youth's developing brain. I also want to explore research that looks critically at incarceration and punitive measures as the primary...

12 August 2024 862 0 View

Strugglling with m6A dot blot any suugesstion ?

I have been doing the m6A dot blot for a while with no improvement, I am extracting the RNA, and I can see the dots although the three biological replicas give a different reading on the memberan...

10 August 2024 8,539 5 View

How can I use the cif data obtained from rietveld refinement extracted via gsas2, for microstructural analysis using ETEX software?

09 August 2024 7,718 0 View

Is this a facetotecta nauplius?

This larva was captured using a plankton net in the Persian Gulf during the summer. I believe it may be a Facetotecta nauplius.

08 August 2024 3,746 4 View

What precautions should be taken while handling S. aureus enterotoxin Type B in the lab?

I would like to understand potential safety concerns while handling SEB in the lab. Especially while working in animal house facility. Would like to know precautions for handling. Sigma MSDS...

07 August 2024 6,034 3 View

How do soil microflora interact with plant roots and influence plant nutrition, health, and productivity?

06 August 2024 9,618 3 View

The aqueous fraction of the hydroethanolic extract is showing the presence of palmitic acid. What is the mechanism responsible ?

Palmitic acid presence in aqueous fraction

05 August 2024 8,624 4 View

For an in-vitro drug release study, what molecular weight cut-off (MWCO) dialysis bag is required for a 117 kDa protein?

kindly reply me. Thanking you in advance.

05 August 2024 7,727 4 View

How to isolate lymphocytes from mouse spleen?

I have tried several times to isolate lymphocytes from mouse spleen, but all attempts have been unsuccessful. I tried most available protocols. I used different dissociation media (HBSS with Ca...

04 August 2024 9,913 7 View

Does long-term culture of murine Monocytes result in macrophage differentiation?

Hi, I am isolating monocytes from the bone marrow using the Mouse Monocyte EasySep kit. I want to treat these cells and monitor expression of specific markers over the course of 10 days. I will...

04 August 2024 7,282 2 View