Anytime you take more than one medication, or even mix it with certain foods, beverages, or over-the-counter medicines, you are at risk of a drug interaction. Most drug interactions are not serious, but because a few are, it is important to understand the possible outcome before you take your medications
DEAR DOCTOR
A drug interaction is a reaction between two (or more) drugs (called a drug-drug interaction) or between a drug and a food or beverage (called a drug-food interaction). An existing medical condition can make certain drugs potentially harmful (called a drug-condition interaction). For example, taking a nasal decongestant if you have high blood pressure may cause an unwanted reaction.
Medicines help us feel better and stay healthy. But drug interactions can cause problems by reducing or increasing the action of a medicine or causing adverse (unwanted) side effects.
REGARDS
Drug interaction is either agonist or antagonist i.e. either increase or decrease the effect of other drugs or substances.
Drug- drug, drug- food and all other interaction of drugs require thorough study. A professional person like a Physician, Veterinarian or Nurse should have sufficient idea on the subject before entering into the field of practice.
These professionals should keep an updated tabulated list of probable drug interactions on the working table.
That subject is termed as Pharmacovigilance.
Drug interactions may make your drug less effective, cause unexpected side effects or increase the action of a particular drug. Some drug interactions can even be harmful to you.
Drug interactions fall into three broad categories:
Drug-drug interactions occur when two or more drugs react with each other.
Drug-food/beverage interactions result from drugs reacting with foods or beverages.
Drug-condition interactions may occur when an existing medical condition makes certain drugs potentially harmful.
Dear Dr.Neeran Jasim
Any substance or medicine, will interfere with a signal or several signals, and thus affect a path or several vital pathways,
The reaction may be positive or negative, and may lead to drug resistance. Pls. find the attached files https://web.bii.a-star.edu.sg/~stanley/Posters/Apoptosis%20pathways%20and%20drug%20targets.pdf
http://www.sugarconebiotech.com/?cat=117 https://www.genome.gov/27530687/ http://www.sciencedirect.com/science/article/pii/S2212492614000554 http://stke.sciencemag.org/content/2004/225/eg5 http://www.nature.com/articles/1204141 http://www.sciencedirect.com/science/article/pii/B9780123944405000188
https://link.springer.com/chapter/10.1007/978-3-642-25761-2_10 Best regards
I agree with Dr Ali Kadhum M. Al-Qurabat. I would like to point out that teas, even the black tea can modify the effectivity of a drug.
I agree with Shibabrata Pattanayak answer in addition I would like to add some.
Drug interactions may be pharmacodynamic type or pharmacokinetic type.
Myself working as a clinical Pharmacist had seen many drug-drug interactions in prescriptions but in my practice I have seen not all the drug-drug interactions are significant enough to cause harm to the patient and in the same way some of the drug-drug interactions go unnoticed because the patient may not complain or any laboratory investigation may be normal, sometimes the effect of interaction may be thought due to the patient's own disease or ailment but not the effect of interacting drugs.
Good discussion indeed!
To supplement what is already mentioned, I would add that drug interactions may be of the following nature:
1. Pharmaceutical interaction (at the chemical level)
2. Pharmacodynamic interaction (at the level of drug action)
3. Pharmacokinetic interaction (one drug altering the effect of the other at the level of absorption, metabolism or excretion)
All the above phenomena can lead to impaired performance of drugs which in turn would affect the therapeutic outcome.
In certain specific situations, however, pharmacodynamic/pharmacokinetic interactions can be therapeutically rational leading to clinical benefits.
I have no idea but i can summerize that each drug acts in opposite way..Thanks and Regards