With my recent personal review of the literature on this topic, there are no new medications that have been shown to improve vertigo with high level of evidence.

Thanks Vincent

See this article by RGacek and consider writing to him:

ORL J. Otorhinolaryngol. Relat. Spec., 2008 vol. 70(1) pp. 6-14; discussion 14-5

Evidence for a viral neuropathy in recurrent vertigo

Gacek, RR

The concept that reactivation of latent neurotropic viruses (i.e. Herpesviridae group) in the vestibular ganglion is responsible for recurrent vestibulopathies is presented. A similar histopathologic degeneration of vestibular ganglion cells in vestibular neuronitis (VN), Ménière's disease and benign paroxysmal positional vertigo is presented to support this concept. The clinical response (relief of vertigo) to the administration of antiviral medication in these syndromes provides practical evidence of a viral neuropathy in patients with recurrent vertigo. Relief of vertigo after this treatment was 90% in VN, Ménière's disease and VN. The relief of positional vertigo (benign paroxysmal positional vertigo) was 66%.

(c) 2008 S. Karger AG, Basel

Address: Department of Otolaryngology-Head and Neck Surgery, University of Massachusetts Medical School, Worcester, MA 01655, USA. [email protected]

There is no uniform cure for vertigo as you know and treatment will depend on the cause of vertigo. Did you mean symptomatic treatment or cure for a specific disease such as Meniere's or BPPV?

See articles by R Gacek, J Vrabec, and others. Meniere's is secondary to recurrent viral vestibular neuritis. See my writing at http://www.tampabayhearing.com/vestibularneuritis.php. Our experience matches Gacek's: the vast majority of Meniere's patients do remarkably better on long term antivirals. Dr Gacek suggests control rates of 85% for Meniere's, 90% for recurrent vestibular neuritis. Learn as well about chronic fluctuating utricular saccular dysfunction.

Our experience is that labyrinthectomy, sac surgery, vestibular nerve section, and even transtympanic gentamicin are needed much less often if long term anti-herpes meds are used: acyclovir, valacyclovir, and famciclovir.

Chemical labyrinthectomy using gentamycin is a very appreciated treatment for curing vertigo in Meniere disease resistant to medical treatment. Otoneurologic tests should be done first including VEMPs, caloric tests and posturography.They allowed to follow the effect of the treatment.

As far as I am aware there is no new treatment for vertigo. Treatment depends on the diagnosis.

Rare form of debilitating vertigo simulating Menieres disease but without hearing loss was cured with acetazolamide 250 to 500 mg daily.