Hello!

I am wondering if there is a software that can predict the effect of a frameshift mutation on protein stability as a monomer/dimer with WT. The mutation is a 2bp deletion and frameshift which results in a slightly truncated protein. I have the sequences of both the WT and mutant (AA and DNA). There is, however, no PDB crystal structure of my protein. Is there any software similar to DynaMut or mCSM-PPI2 that can give me a ΔΔG prediction? Thank you!

Nellie