Does anybody know the sequence of an anti-human beta-2 microglobulin nanobody or antibody that binds to the MHC I/b2M heretodimer? Not just to free b2M.
antibody
Dear Dirk,
There are some nanobodies that have been produced against b2m but most have been screened on amyloid forms e.g
Article A specific nanobody prevents amyloidogenesis of D76N β2-micr...
You could use also the W6/32 sequence as described in the paper
Article Production and characterization of chimeric anti-HLA monoclo...
We also sequenced the hybridoma and confirmed this sequence.
If you want an expression construct i can ask someone in Hannover to look in my old boxes.
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