Hello Silvia, 

In my country, India, 3 different genotypes are well established- A, C and D. Of these genotypes, subgenotype A1, A2, Cs, D1, D2, D3 and D5. We reported D5 for the first time.

Please search the NCBI pubmed with my name and you will get a number of paper related to your query. If you need full texts of any of them, please let me know. I am also attaching a review which might help you further.

If you need more information, Please let me know, I will be happy to help you in your efforts.

Best regards,

Dr Sibnarayan Datta

Thank you Sib

Important your information about A2, Cs -will find which ones-, D1, D2, D3.

D5 as very characteristic in your contry.

Thanks again

Silvia

Vast majority of Saudi patients with chronic hepatitis B have genotype D

http://www.ncbi.nlm.nih.gov/pubmed/17109498.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530988

The same is true for Pakistan where Genotype D is detected as the most prevalent

(58.5%)   followed by  mix  genotype A and D (31.5%)  and genotype A was only  (10%)

Hanif et al., 2013 African Journal of Microbiology Research Vol. 7(3), pp. 152-157, 15January 2013.

http://jpma.org.pk/full_article_text.php?article_id=1622

Dr Ishtiaq Qadri

Thank you for your information about prevalent HBV genotype in Pakistan  and for sending the article source

Regards

Dear Dr. Sibnarayan  Datta

Could you send the accession numbers or gi for indian HBV genotypes to be included in our MSA , interesting as these not represent a high risk for HCC.  Thank you

Dear Dr Silvia,

Please go through the following link and download the required sequences. Please note that these are all complete genome sequences, and these count 365 till date. some of the recent entries are done on next generation sequencer.  There are also a numerous partial gene sequences for S, PreS, X, C/ preC, in addition to the complete genome. You will get representative complete genome for all the subgenotypes detected in India, till now. In all the sequences submitted from our laboratory, we have included the subgenotype information. However, in some of the sequences submitted from other labs, subgenotype information may not be present. I believe that including representative complete genomes from India will suffice your requirement. 

http://www.ncbi.nlm.nih.gov/nuccore/?term=human+hepatitis+B+virus+complete+genome+India

Please let me know if I can be of any other help to you in this study.

Best regards,

SD

Thank yo Dr. Sib

"sharing knowledge is critical for progress"  Rehma Chandaria

Thank you Dr Silvia. :-)

SD

Very welcome Dr. Sibnarayan Datta

Regards

Silvia

Until date, India reports 365 human hepatitis B virus complete genomes and Peru reports 3

Dr Sibnarayan

Could you explain the classification of this genome DQ315783.1 GI:87295395 as Cs

Thank you for your answer

Dear Silvia,

DQ315783 was classified as HBV subgenotype Cs/C1 based on the detailed phylogenetic relatedness of the sequence with well established reference sequences retrieved from the GenBank at that time (time of submission). In fact the Surface and Core gene sequences (Banerjee-World J Gastroenterol-2006), the X gene sequence (Datta-Virology-2008) as well as the complete genome (Banerjee-J Med Virol- 2006) was analyzed and found to be related to Cs/C1 subgenotype of HBV.

I am attaching the 3 papers for your kind perusal and reference. Please note that, in all these 3 papers, the sequence is identified by the isolate number 'EI03188' in the Cs/C1 cluster of the phylogenetic trees. 

I hope I could explain.. 

regards

Sib

Thank you for your answer Dr Sib

Regards

Silvia

Thanks Dr Silvia :-)

Sib

Genotype F circulates in the peruvian andean population -PERU-, with the serological subtype adw4, being specific the subtype F1c.

To Dr Sibnarayan Datta

Which is the prevalence of HBV in your country? Which is the incidence of HCC?

Thank you for your consideration to this question?