Dear Paola, 

to my opinion it should be possible to induce EAE in C57Bl/6 mice without irradiation, as the strain is relatively susceptible to EAE, and to my knowledge the irradiation (

Dear Paola, 

to my opinion it should be possible to induce EAE in C57Bl/6 mice without irradiation, as the strain is relatively susceptible to EAE, and to my knowledge the irradiation (

Dear Michael,

Thank you very much for your answer. Actually, my protocol involves the usage of IL-23 and anti-IFN-gamma. I will do the restimulation in the next few days, I will post how it works :-)

Interesting! Keep us informed ☺