In his work "Letters from the philosophy of empirical sciences" in which Imre Lakatos raises the problem of demarcation in how to distinguish science from non-science, proposes to solve in this way and establish the following demarcation criterion. Namely, science based theses on its research methods, and non-science is based on falsehood. How to distinguish the thesis from falsehood deals with epistemology, methodology and methodology. In short, science deals with the study of nature and states thesis, unscientific or pseudoscience falls into falsehood.