Please tell me the solvent which can completely dissolve Hydroxyapatite (HAp) for biomedical coating other than acids?
Actually the terminology is wrong, if completely soluble means, it produces only the ions in the solution. The terminology is dispersion, Normally Iso propyle acohol (IPA), acetone and ethanol are best solvent to disperse the HAP and need sonnication and ageing for a day. then u have take that solution and do the coating by EPD. Otherwise u have prepare the precursor in the solution form and do the coatings. then give the alkaline treatments and sintering to convert the calcium phosphate into HAp. Please go through the papers.
From what I can remember from my time making toothpaste formulations that slow released calcium from nanoparticles, you don't completely dissolve hydroxyapatite. You either precipitate it from the start materials in situ or you use a suspension of particles.
Actually the terminology is wrong, if completely soluble means, it produces only the ions in the solution. The terminology is dispersion, Normally Iso propyle acohol (IPA), acetone and ethanol are best solvent to disperse the HAP and need sonnication and ageing for a day. then u have take that solution and do the coating by EPD. Otherwise u have prepare the precursor in the solution form and do the coatings. then give the alkaline treatments and sintering to convert the calcium phosphate into HAp. Please go through the papers.
Thanks Andrew Kirkham & Shanmugam ss for your valuable information. I will go through the papers.
can you dissolve hydroapatite deposits in the rotator cuff area?
Jaime,
When I was younger I used to have chronic knee pain. The physiotherapist used to use a sonic probe pushed up under the lower end of my patella to break up what she described as "deposits". I'd assumed these were a combination of HAP and cartilage.
As for solvents for minerals, it depends what you want to do with them. You can dissolve any mineral in the right solvent (usually an acid or a base), but that tends to destroy them. As Shanmugam states above, what you probably want to do is disperse them. In which case, organic solvents are the place to start.
A solution of disodium EDTA- DI water is useful. You need to go through literature to decide on the best concentration for your need.
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