The answer to your question cannot be provided in general terms and depends very much on numerous influencing parameters.

 Some of those parameters are:

• the size of “large scale” (50 liter, 500 liter, 5000 liter, 50000 liter, 500000 liter or larger),
• the used algae species,
• intended use of wild-type or genetically modified organisms,
• financial possibilities,
• energy availability,
• extent of water supply,
• type of water (salinity, pH, with/without contaminations, wastewater…),
• non-sterile, semi-sterile or axenic cultivation,
• possible land use and other environmental impacts,
• available culture medium/nutrients,
• solar incidence (if outdoor culture),
• possible cell density based on the above factors,
• suitability of diverse reactors/ponds in regards to the above factors,
• type of intended harvesting method,
• type of intended extraction method,
• required purity of the products,
• production for commercial use or based on scientific issues
• etc.

 There is a large literature dealing with this topic.

 Here is just a small selection of references:

• Hallmann A. Algae biotechnology – Green cell-factories on the rise. Curr Biotechnol. 2015;4(4):389-415.
• Han SF, Jin WB, Tu RJ, Wu WM. Biofuel production from microalgae as feedstock: current status and potential. Crit Rev Biotechnol. 2015;35(2):255-68.
•  Posten C. Design principles of photo-bioreactors for cultivation of microalgae. Eng Life Sci. 2009;9(3):165-77.
• Jones CS, Mayfield SP. Algae biofuels: versatility for the future of bioenergy. Curr Opin Biotechnol. 2012;23(3):346-51.
• Gim GH, Kim JK, Kim HS, Kathiravan MN, Yang H, Jeong SH et al. Comparison of biomass production and total lipid content of freshwater green microalgae cultivated under various culture conditions. Bioprocess Biosyst Eng. 2014;37(2):99-106.
• Markou G, Nerantzis E. Microalgae for high-value compounds and biofuels production: a review with focus on cultivation under stress conditions. Biotechnol Adv. 2013;31(8):1532-42.
• Blatti JL, Michaud J, Burkart MD. Engineering fatty acid biosynthesis in microalgae for sustainable biodiesel. Curr Opin Chem Biol. 2013;17(3):496-505.
• Sharma KK, Schuhmann H, Schenk PM. High lipid induction in microalgae for biodiesel production. Energies. 2012;5:1532-53.
• Alam F, Date A, Rasjidina R, Mobinb S, Moria H, Baqui A. Biofuel from algae - Is it a viable alternative? Procedia Engineering. 2012;49:221-7.
• Halim R, Danquah MK, Webley PA. Extraction of oil from microalgae for biodiesel production: A review. Biotechnol Adv. 2012;30(3):709-32.
• Pandey A, Lee D-J, Chisti Y, Soccol CR. Biofuels from algae, 1 edition (October 21, 2013) edn: Elsevier; 2013.
• Verma NM, Mehrotra S, Shukla A, Mishra BN. Prospective of biodiesel production utilizing microalgae as the cell factories: A comprehensive discussion. Afr J Biotechnol. 2010;9(10):1402-11.
• Andersen RA. Algal culturing techniques. Amsterdam: Elsevier; 2005.
• Medipally SR, Yusoff FM, Banerjee S, Shariff M. Microalgae as sustainable renewable energy feedstock for biofuel production. BioMed research international. 2015;2015:519513.
• Mutanda T, Ramesh D, Karthikeyan S, Kumari S, Anandraj A, Bux F. Bioprospecting for hyper-lipid producing microalgal strains for sustainable biofuel production. Bioresour Technol. 2011;102(1):57-70.
• Chen CY, Yeh KL, Aisyah R, Lee DJ, Chang JS. Cultivation, photobioreactor design and harvesting of microalgae for biodiesel production: a critical review. Bioresour Technol. 2011;102(1):71-81.
• Awasthi M, Singh RK. Development of algae for the production of bioethanol, biomethane, biohydrogen and biodiesel. International Journal of Current Science. 2011;1:14-23.
• Malcata FX. Microalgae and biofuels: a promising partnership? Trends Biotechnol. 2011;29(11):542-9.
• Day JG, Slocombe SP, Stanley MS. Overcoming biological constraints to enable the exploitation of microalgae for biofuels. Bioresour Technol. 2012;109:245-51.
• Radakovits R, Jinkerson RE, Darzins A, Posewitz MC. Genetic engineering of algae for enhanced biofuel production. Eukaryot Cell. 2010;9(4):486-501.
• Brennan L, Owende P. Biofuels from microalgae - A review of technologies for production, processing, and extractions of biofuels and co-products. Renewable and Sustainable Energy Reviews. 2010;14:557–77.
• Rodolfi L, Chini Zittelli G, Bassi N, Padovani G, Biondi N, Bonini G et al. Microalgae for oil: strain selection, induction of lipid synthesis and outdoor mass cultivation in a low-cost photobioreactor. Biotechnol Bioeng. 2009;102(1):100-12.

You can refer Algal Culturing Techniques by Robert. A. Andersen you will get some idea from isolation to large-scale cultivation of microalgae.

The answer to your question cannot be provided in general terms and depends very much on numerous influencing parameters.

 Some of those parameters are:

• the size of “large scale” (50 liter, 500 liter, 5000 liter, 50000 liter, 500000 liter or larger),
• the used algae species,
• intended use of wild-type or genetically modified organisms,
• financial possibilities,
• energy availability,
• extent of water supply,
• type of water (salinity, pH, with/without contaminations, wastewater…),
• non-sterile, semi-sterile or axenic cultivation,
• possible land use and other environmental impacts,
• available culture medium/nutrients,
• solar incidence (if outdoor culture),
• possible cell density based on the above factors,
• suitability of diverse reactors/ponds in regards to the above factors,
• type of intended harvesting method,
• type of intended extraction method,
• required purity of the products,
• production for commercial use or based on scientific issues
• etc.

 There is a large literature dealing with this topic.

 Here is just a small selection of references:

• Hallmann A. Algae biotechnology – Green cell-factories on the rise. Curr Biotechnol. 2015;4(4):389-415.
• Han SF, Jin WB, Tu RJ, Wu WM. Biofuel production from microalgae as feedstock: current status and potential. Crit Rev Biotechnol. 2015;35(2):255-68.
•  Posten C. Design principles of photo-bioreactors for cultivation of microalgae. Eng Life Sci. 2009;9(3):165-77.
• Jones CS, Mayfield SP. Algae biofuels: versatility for the future of bioenergy. Curr Opin Biotechnol. 2012;23(3):346-51.
• Gim GH, Kim JK, Kim HS, Kathiravan MN, Yang H, Jeong SH et al. Comparison of biomass production and total lipid content of freshwater green microalgae cultivated under various culture conditions. Bioprocess Biosyst Eng. 2014;37(2):99-106.
• Markou G, Nerantzis E. Microalgae for high-value compounds and biofuels production: a review with focus on cultivation under stress conditions. Biotechnol Adv. 2013;31(8):1532-42.
• Blatti JL, Michaud J, Burkart MD. Engineering fatty acid biosynthesis in microalgae for sustainable biodiesel. Curr Opin Chem Biol. 2013;17(3):496-505.
• Sharma KK, Schuhmann H, Schenk PM. High lipid induction in microalgae for biodiesel production. Energies. 2012;5:1532-53.
• Alam F, Date A, Rasjidina R, Mobinb S, Moria H, Baqui A. Biofuel from algae - Is it a viable alternative? Procedia Engineering. 2012;49:221-7.
• Halim R, Danquah MK, Webley PA. Extraction of oil from microalgae for biodiesel production: A review. Biotechnol Adv. 2012;30(3):709-32.
• Pandey A, Lee D-J, Chisti Y, Soccol CR. Biofuels from algae, 1 edition (October 21, 2013) edn: Elsevier; 2013.
• Verma NM, Mehrotra S, Shukla A, Mishra BN. Prospective of biodiesel production utilizing microalgae as the cell factories: A comprehensive discussion. Afr J Biotechnol. 2010;9(10):1402-11.
• Andersen RA. Algal culturing techniques. Amsterdam: Elsevier; 2005.
• Medipally SR, Yusoff FM, Banerjee S, Shariff M. Microalgae as sustainable renewable energy feedstock for biofuel production. BioMed research international. 2015;2015:519513.
• Mutanda T, Ramesh D, Karthikeyan S, Kumari S, Anandraj A, Bux F. Bioprospecting for hyper-lipid producing microalgal strains for sustainable biofuel production. Bioresour Technol. 2011;102(1):57-70.
• Chen CY, Yeh KL, Aisyah R, Lee DJ, Chang JS. Cultivation, photobioreactor design and harvesting of microalgae for biodiesel production: a critical review. Bioresour Technol. 2011;102(1):71-81.
• Awasthi M, Singh RK. Development of algae for the production of bioethanol, biomethane, biohydrogen and biodiesel. International Journal of Current Science. 2011;1:14-23.
• Malcata FX. Microalgae and biofuels: a promising partnership? Trends Biotechnol. 2011;29(11):542-9.
• Day JG, Slocombe SP, Stanley MS. Overcoming biological constraints to enable the exploitation of microalgae for biofuels. Bioresour Technol. 2012;109:245-51.
• Radakovits R, Jinkerson RE, Darzins A, Posewitz MC. Genetic engineering of algae for enhanced biofuel production. Eukaryot Cell. 2010;9(4):486-501.
• Brennan L, Owende P. Biofuels from microalgae - A review of technologies for production, processing, and extractions of biofuels and co-products. Renewable and Sustainable Energy Reviews. 2010;14:557–77.
• Rodolfi L, Chini Zittelli G, Bassi N, Padovani G, Biondi N, Bonini G et al. Microalgae for oil: strain selection, induction of lipid synthesis and outdoor mass cultivation in a low-cost photobioreactor. Biotechnol Bioeng. 2009;102(1):100-12.

I cannot add to the answers already given. To be helpful I need the orgasm wanting t be grow and the enduse of of the biomass

Hallo Dr. Natarajan Mohan, Armin Hallmann and Keith E Cooksey,

Thank you for your advice and references.

Once you have grown your cells you will need to harvest them, and this can be a major energetic and economic challenge.

MILLEDGE, J. J. & HEAVEN, S. 2013. A review of the harvesting of micro-algae for biofuel production. Reviews in Environmental Science and Biotechnology, 12, 165-178.