I read your interesting article and I see that you especially mention severe pathologies such as diarrhea in case of immunodeficiency and malnutrition.
Data Risk factors associated with Cryptosporidium oocyst (to revise)
Cryptosporidiosis remains a potentially serious disease in vulnerable people. In immunocompromised HIV positive or not, cryptosporidiosis is part of opportunist infections. After an acute phase where the parasite is located in the intestinal lumen, Cryptosporidiosis can enter a phase of chronicity in immunocompromised patients and invade the hepatobiliary routes. Several episodes of reinfection can be observed.
Of pulmonary cryptosporidiosis have been reported in HIV positive patients with CD4 T lymphocyte count below 50/mm3.
Due to lack of tissue specificity, C. parvum infection has also been identified in the biliary tract (causing thickening of the gallbladder wall) and the respiratory system (Casemore, et al., 1994).
I thank you Dr for your answer. Pancreatitis is also a common severe pathology encountered in cryptosporidium infection. But i don't find in literature if it can happen late or spontaneously after infection
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