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Daniel Bereczki

Hi Atte,

I would vote for the Wahlund score.

A New Rating Scale for Age-Related White Matter Changes Applicable to MRI and CT

Stroke 2001; 32: 1318-1322

Bo Norrving

Atte: by us we have used this one. I know of none better - but others may add to this. Best regards from Bo

Wahlund LO, Barkhof F, Fazekas F, Bronge L, Augustin M, Sjögren M, Wallin A, Ader H, Leys D, Pantoni L, Pasquier F, Erkinjuntti T, Scheltens P; European Task Force on Age-Related White Matter Changes. A new rating scale for age-related white matter changes applicable to MRI and CT. Stroke. 2001 Jun;32(6):1318-22.

Floris Schreuder

Dear Atte,

The best review that you can find on this topic was published 1.5 year ago in Lancet Neurology, which is an excellent overview on how to approach small vessel disease:

Wardlaw e.a. Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration. Lancet Neurol. 2013 Aug;12(8):822-38.

Kind regards,

Floris

http://www.sciencedirect.com/science/article/pii/S1474442213701248

Rustam Al-Shahi Salman

As the others say, the Wahlund scale is one good option. Following STRIVE's recommendations is the right way to go. Joanna Wardlaw has also nicely summarised the available tools here: http://www.bric.ed.ac.uk/research/imageanalysis.html#wmlr

Best wishes,

Rustam

Atte Meretoja

Thanks a lot everyone!

I had previously looked at the older van Swieten method http://jnnp.bmj.com/content/53/12/1080.long

but clearly the Wahlund scale is more popular (annual citations 15 vs 100).

All the best,

Atte