Willett WC, M.D., David S. Ludwig DS, in an article titled ‘Milk and Health’ published in ‘N Engl J Med 2020; 382:644-654 opined that "Among men, milk intake during adolescence was linearly associated with a 9% greater risk of hip fracture later in life for every additional glass consumed per day. No association with the risk of hip fracture was seen among women." What could be the possible explanations?
Md. Zakirul Islam
Milk intake and risk of mortality and fractures in women and men
- High milk intake is recommended for the prevention of osteoporotic fractures.
- Milk is the major dietary source of galactose intake.
- The addition of galactose by injection or in the diet is an established animal model of aging by induction of oxidative stress and inflammation.
- Results of previous research on the importance of milk intake for the prevention of fractures and the influence on mortality rates are conflicting.
- High milk intake in both sexes is associated with higher mortality and fracture rates and with higher levels of oxidative stress and inflammatory biomarkers.
- Such a pattern was not observed with a high intake of fermented milk products.
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Harasit Kumar Paul
Thanks Md. Zakirul Islam for your interest in the topic and valued addition to the discussion.
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