Provisional research diagnostic criteria for Mild Behavioral Impairment (MBI)

A. Behavioral concern reflecting a change in behavior observed by patient or informant or clinician, starting later in life (age≥50) and persisting at least intermittently for > 3 months. These represent clear change from the person’s usual behavior as evidenced by at least one of the following:

a. Decreased motivation (e.g. apathy, aspontaneity, indifference)

b. Affective lability (e.g. anxiety, dysphoria, changeability, euphoria, irritability)

c. Impulse dyscontrol (e.g. agitation, disinhibition, gambling, obsessiveness, behavioral perseveration, stimulus bound)

d. Social inappropriateness (e.g. lack of empathy, loss of insight, loss of social graces or tact)

e. Abnormal perception or thought content (e.g. delusions, hallucinations)

B. Behaviors are of sufficient severity to produce disability in at least one of the following areas:

a. Interpersonal relationships

b. Other aspects of social functioning

c. Ability to perform in the workplace

C. While co-morbid conditions may be present, the behavioral changes are not attributable to another psychiatric disorder, or vascular, traumatic or medical causes, or the physiological effects of a substance or medication.

D. The patient does not meet criteria for a dementia syndrome (e.g., Alzheimer’s dementia, frontotemporal dementia, dementia with Lewy bodies, vascular dementia, other dementia). Mild Cognitive Impairment can be concurrently diagnosed with Mild Behavioral Impairment.

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