I found many studies about virus detection by Surface Enhanced Raman Absorption Spectroscopy (SERS) but is it possible by SEIRAS?
Very nice question, I would be also looking for an appropriate answer.
I can't say for definite but it may be that because SEIRAS is not as sensitive as SERS, it has not generally been favoured as a technique and as such there is less literature on it however I did find a paper.
While the paper I am linking you to does not mention viruses themselves, it does discuss nucleic acid studies using SEIRAS. I hope this paper is useful to you:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1839866/
Derek.
Really I don't know, but seeketh information concerning this subject. sounds very interesting
I think the main hindrance of applying SEIRAS to biomedical detection is the modest enhancement factor (10E1 - 10E3) as compared to the enormous enhancement factor (10E6 - 10E12) of SERS.
Correct Changji, my reading would suggest the same issue with SEIRAS. Further to this, the main applications of SEIRAS appear to be in electrochemistry and not biomedical detection. However, as I previously described, this may be because there is simply less interest, as a community, in SEIRAS over SERS.
In attachment publication on Bovine LEUKEMIA VIRUS detection.
Article Magnetic Gold Nanoparticles in SERS-Based Sandwich Immunoass...
Thank you Prof. Ramanavicius , and beside Changji Zou and Derek Connor although the enhancement factor of SERS is bigger than SEIRAS , the cross-section for IR absorption is several orders of magnitude higher than the Raman cross-section and this enhancement factor of SEIRAS may be sufficient for many applications
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