Is it possible to get a particular form of tautomer at a particular temperature?
The ratio of the tautomers depends on different factors including temperature. At some temperatures both tautomers are present in solution but at special temperature one tautomer is predominate. The changes in ratios can be investigated by NMR spectroscopy.
The ratio of the tautomers depends on different factors including temperature. At some temperatures both tautomers are present in solution but at special temperature one tautomer is predominate. The changes in ratios can be investigated by NMR spectroscopy.
As was already mentioned. Moreover, you can calculate the relative energy between tautomers by VT 1H NMR. See for example: J. Chem. Soc., Perkin Trans. 2, 2185-2191 (2000).
Tautomerism is an equilibrium. Depending on conditions you can have your equilibrium more or less shifted towards one side. pH, solvents, etc. are better suitted for that purpose.
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