Mineral trioxide aggregate (MTA) is a biomaterial used for root-end filling, perforation repair, internal and external resorption, vital pulp therapy and apical barrier formation for teeth with necrotic pulps and open apices. Recently MTA based sealers have opened up the horizon for root canal sealers. Sealers based on MTA have been reported to be biocompatible, stimulate mineralization and encourage apatite-like crystalline deposits along the apical- and middle-thirds of canal walls.

Calcium enriched mixture (CEM) cement, Biodentin, Bioaggregate, and EndoSequence Root Repair Material (ERRM) and EndoSequence BC Sealer have been introduced to the market recently. Is there any difference in the indications, clinical applications and success rate of MTA, biodentine and CEM cement in endodontic uses?

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