oes anyone know if I want to immunize Lewis rats with lacrimal antigens, whether it is important to use lacrimal extract from a different species like SD rats, or even from C57B6 mice?
Our experience has been that one can immunize with antigens of the same species.
In 1992, Liu & Zhou reported purification of a bovine lacrimal gland protein that elicited lacrimal gland disease in rat and murine lacrimal glands. Antiserum to the bovine LGAg cross-reacted with an Ag in murine LG.