Is it possible to use only ten samples in the research, knowing that my samples are cases of extracting teeth and then drawing blood to isolate bacteria and it is difficult to obtain the consent of patients to draw blood.
The general rule, the higher number of samples lead to higher analysis accuracy. I think 10 sample is not enough for scientific studying usually 30 to 300 samples are suitable number for most types of research. Yes, there are some exceptions, depending on the ability to obtain samples. please find attachment for more details