Hi All

I recently done a Systematic review and checked the quality of methodology of the included studies (almost 30 in number) for the effect of intervention by Down's and Black quality assessment tool. However, there were not a single study with high quality.

My main questions are:

1. Is it okay to continue SR without any meta analysis as there are not any high quality studies seen through Down's and Black quality assessment tool? If so, is there any article for the justification, will be greatly appreciated.

2. Is it possible to do the meta analysis of only moderate quality studies rather than including all other low quality studies in the same Systematic review?

Thanks, and regards

Preet

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