Considering that organic selenium (as seleno-methionine) is not metabolically differentiated from sulfur-methionine, is it possible that this substitution occurs also on Fe-S proteins at the Complex I and II of of mitochondrial electron transport?
Yes, I think it can be possible! because Se replaces S in certain molecules. But probably this phenomenon could be more obvious when Se is present in high concentration in environment.
I think so. I have been working with plant treated with Se. and what I found when certain plant species are treated with high concentration of Se the total concentration of S (in acid digested samples) is affected negatively in above ground plant parts and plants protein contents are also affected by supplementation with high Se content in soil.