Is it common or uncommon to find a normal leukocyte count during the exanthem phase of a measles infection?

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Ziad A Audat

It is uncommon to find normal leukocyte count.

Measure an interferon-induced enzyme in white blood cells

Andrew A Mahony

Lymphopenia is very common in measles infection. The virus infects specific lymphocytes, and an immunosuppressed-like state can last for several weeks. The following articles from PubMed give more details:

Clin Exp Immunol. 1978 June; 32(3): 540–544. PMCID: PMC1541324Immunological recovery after measles.

A Wesley, H M Coovadia, and L Henderson

PLoS Pathog. 2012;8(8):e1002885. doi: 10.1371/journal.ppat.1002885. Epub 2012 Aug 30.

Measles immune suppression: lessons from the macaque model.

de Vries RD, McQuaid S, van Amerongen G, Yüksel S, Verburgh RJ, Osterhaus AD, Duprex WP, de Swart RL.