I do not have any experience with evaluation of GI cancers, but I do have a more than average training in histology. My reaction to your question would be to ask you: with what treatment/stain are you most familiar? Because the exact molecular mechanisms of these stains are not known, it is your own expertise that will make the difference. My advise would be to use the stain that you are familiar with, and deal with the bad/good economics of your choice. Kind regards, Harrie Verhoeven.