In the March 5 update of the project "Prescriptive ontology in the Hebrew Bible", the resonant interaction of a number N of two level systems (TLS) in a cavity with an electro-magnetic field at a cavity mode frequency was discussed . When the transitions from the lower to the upper level of the TLS are in phase, the interaction energy is largest and the in phase oscillating system is the polariton Bose-Einstein condensate. It can occur at ambient temperature because it is stabilized by the matter-field interaction, which occurs in the strongly coupled, robust, pumped polariton condensates but not in systems composed of matter alone, such as the fragile Fröhlich condensates . At high interaction energies, optics becomes non-linear, The TLS oscillates between the upper state and the lower state at the Rabi frequency, by emission and re-absorption of resonant photons. The Rabi frequency is equal to the light- TLS interaction energy of the Bose-Einstein condensate divided by Planck's constant.

In microtubules, at the cavity mode resonance, the interaction energy of the polariton condensate is largest, not only because of the large Rabi frequency but also because of the strong induced dipole-dipole interaction between tubulin rings. This leads to an interesting polariton-condensation-induced chemical effect: the increase of the length of the microtubule molecule by polymerization of tubulin. The maximum effect of microtubule lengthening is obtained at the electromagnetic field frequency which resonates with the cavity mode frequency. Changing the cavity dimensions will change the electromagnetic field frequency producing maximum microtubule lengthening. Electromagnetically-induced polymerization of neuron tubulin in a cavity was obtained in 2014 by Bandyopadhyay et al, without noticing that thereby they introduced polariton chemistry; see https://www.nature.com/articles/srep07303.pdf This discovery can lead to new treatments of Parkinson's disease and other brain disorders, as was noted by Stuart Hameroff in his YouTube presentations.

The question presented here is whether cavity polariton polymerization is a general mechanism in biology.